RRC ID 30762
著者 Yoshida T, Kawabe A.
タイトル Importance of gene duplication in the evolution of genomic imprinting revealed by molecular evolutionary analysis of the type I MADS-box gene family in Arabidopsis species.
ジャーナル PLoS One
Abstract The pattern of molecular evolution of imprinted genes is controversial and the entire picture is still to be unveiled. Recently, a relationship between the formation of imprinted genes and gene duplication was reported in genome-wide survey of imprinted genes in Arabidopsis thaliana. Because gene duplications influence the molecular evolution of the duplicated gene family, it is necessary to investigate both the pattern of molecular evolution and the possible relationship between gene duplication and genomic imprinting for a better understanding of evolutionary aspects of imprinted genes. In this study, we investigated the evolutionary changes of type I MADS-box genes that include imprinted genes by using relative species of Arabidopsis thaliana (two subspecies of A. lyrata and three subspecies of A. halleri). A duplicated gene family enables us to compare DNA sequences between imprinted genes and its homologs. We found an increased number of gene duplications within species in clades containing the imprinted genes, further supporting the hypothesis that local gene duplication is one of the driving forces for the formation of imprinted genes. Moreover, data obtained by phylogenetic analysis suggested "rapid evolution" of not only imprinted genes but also its closely related orthologous genes, which implies the effect of gene duplication on molecular evolution of imprinted genes.
巻・号 8(9)
ページ e73588
公開日 2013-1-1
DOI 10.1371/journal.pone.0073588
PII PONE-D-13-20983
PMID 24039992
PMC PMC3764040
MeSH Arabidopsis / classification Arabidopsis / genetics* Arabidopsis Proteins / classification Arabidopsis Proteins / genetics* Chromosome Mapping Chromosomes, Plant / genetics Cloning, Molecular Evolution, Molecular* Gene Duplication* Genome, Plant / genetics Genomic Imprinting* MADS Domain Proteins / classification MADS Domain Proteins / genetics* Molecular Sequence Data Phylogeny Sequence Analysis, DNA Species Specificity
IF 2.74
引用数 10
WOS 分野 GENETICS & HEREDITY
リソース情報
シロイヌナズナ / 植物培養細胞・遺伝子 sjs00500