| RRC ID |
30840
|
| 著者 |
Sawamura K, Yamamoto MT, Watanabe TK.
|
| タイトル |
Hybrid lethal systems in the Drosophila melanogaster species complex. II. The Zygotic hybrid rescue (Zhr) gene of D. melanogaster.
|
| ジャーナル |
Genetics
|
| Abstract |
Hybrid females from Drosophila simulans females x Drosophila melanogaster males die as embryos while hybrid males from the reciprocal cross die as larvae. We have recovered a mutation in melanogaster that rescues the former hybrid females. It was located on the X chromosome at a position close to the centromere, and it was a zygotically acting gene, in contrast with mhr (maternal hybrid rescue) in simulans that rescues the same hybrids maternally. We named it Zhr (Zygotic hybrid rescue). The gene also rescues hybrid females from embryonic lethals in crosses of Drosophila mauritiana females x D. melanogaster males and of Drosophila sechellia females x D. melanogaster males. Independence of the hybrid embryonic lethality and the hybrid larval lethality suggested in a companion study was confirmed by employing two rescue genes, Zhr and Hmr (Hybrid male rescue), in doubly lethal hybrids. A model is proposed to explain the genetic mechanisms of hybrid lethalities as well as the evolutionary pathways.
|
| 巻・号 |
133(2)
|
| ページ |
307-13
|
| 公開日 |
1993-2-1
|
| DOI |
10.1093/genetics/133.2.307
|
| PMID |
8436277
|
| PMC |
PMC1205321
|
| MeSH |
Animals
Drosophila melanogaster / embryology
Drosophila melanogaster / genetics*
Drosophila melanogaster / growth & development
Embryo, Nonmammalian
Female
Genes, Insect*
Genes, Lethal*
Genes, Suppressor
Hybridization, Genetic / genetics*
Larva
Male
|
| IF |
4.015
|
| 引用数 |
102
|
|
WOS 分野
|
GENETICS & HEREDITY
|
| リソース情報 |
| ショウジョウバエ |
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