RRC ID 30841
Author Sawamura K, Fujita A, Yokoyama R, Taira T, Inoue YH, Park HS, Yamamoto MT.
Title Molecular and genetic dissection of a reproductive isolation gene, zygotic hybrid rescue, of Drosophila melanogaster.
Journal Jpn. J. Genet.
Abstract Hybrids from the cross between males of Drosophila melanogaster and females of its sibling species (D. simulans, D. mauritiana, or D. sechellia) are embryonic lethal when they carry the wild type allele of zygotic hybrid rescue (zhr) from D. melanogaster. The zhr gene has been mapped in the proximal region of the X heterochromatin slightly distal to the proximal breakpoint of In(1)sc8, the region rich in 1.688 g/cm3 satellite DNA. Since this satellite DNA does not exist in the sibling species, the satellite DNA was considered to be involved in the hybrid lethality. We examined the hypothesis molecular cytogenetically. The results are (1) three Df(1)zhr chromosomes carried this satellite DNA, and (2) hybrids were viable even if the amount of the satellite DNA in hybrids was increased by adding minichromosomes Dp(1;f)1205 and Dp(1;f)1187 into the genome. These results do not support the above hypothesis.
Volume 70(2)
Pages 223-32
Published 1995-4
PMID 7605674
MeSH Alleles Animals Base Sequence Blotting, Southern Chromosome Mapping Chromosomes / chemistry Chromosomes / genetics Crosses, Genetic DNA, Satellite / genetics Dosage Compensation, Genetic Drosophila melanogaster / genetics* Female Genes, Insect* Genes, Lethal Genome Hybridization, Genetic / genetics* In Situ Hybridization Male Molecular Sequence Data
Times Cited 10