| RRC ID |
3157
|
| 著者 |
Murata Y, Sano A, Ueda Y, Inomata T, Takayama A, Poonwan N, Nanthawan M, Mikami Y, Miyaji M, Nishimura K, Kamei K.
|
| タイトル |
Molecular epidemiology of canine histoplasmosis in Japan.
|
| ジャーナル |
Med Mycol
|
| Abstract |
A recent case of canine histoplasmosis, the first confirmed case of disseminated infection accompanied by carcinoma in Japan, was diagnosed by clinical characteristics, histopathological examination, chest radiographs, ocular fundoscopy and molecular biological data. The clinical manifestations were not limited to cutaneous symptoms but were referable to disseminated infection, similar to human autochthonous cases. The partial sequences of the internal transcribed spacer (ITS1/2) regions of the ribosomal DNA genes of this and other Japanese canine histoplasmosis strains were 99-100% identical to the sequence AB211551 derived from a human isolate in Thailand, and showed a close relationship to the sequences derived from Japanese autochthonous systemic and cutaneous human cases. The phylogenetic analysis of 97 sequences of the ITS1/2 region disclosed six genotypes. The genotypes derived from Japanese autochthonous human and dog cases belonged to the cluster consisting of Histoplasma capsulatum var. capsulatum and H. capsulatum var. farciminosum sequences, indicating that these varieties might cause not only cutaneous but also systemic histoplasmosis, regardless of their host species. The current status of the 3 varieties of Histoplasma capsulatum according to the host species remains a subject of further investigation.
|
| 巻・号 |
45(3)
|
| ページ |
233-47
|
| 公開日 |
2007-5-1
|
| DOI |
10.1080/13693780601186069
|
| PII |
777710407
|
| PMID |
17464845
|
| MeSH |
Animals
Choroiditis / pathology
DNA, Fungal / chemistry
DNA, Fungal / genetics
DNA, Ribosomal Spacer / chemistry
DNA, Ribosomal Spacer / genetics
Dog Diseases / diagnosis
Dog Diseases / epidemiology
Dog Diseases / microbiology*
Dog Diseases / pathology
Dogs
Extremities / pathology
Female
Fundus Oculi
Histocytochemistry
Histoplasma / classification*
Histoplasma / genetics
Histoplasma / isolation & purification*
Histoplasmosis / epidemiology
Histoplasmosis / microbiology
Histoplasmosis / pathology
Histoplasmosis / veterinary*
Japan / epidemiology
Lung / diagnostic imaging
Lung / pathology
Male
Molecular Epidemiology*
Molecular Sequence Data
Ophthalmoscopy
Phylogeny
Radiography
Sequence Analysis, DNA
Sequence Homology, Nucleic Acid
Skin / pathology
|
| IF |
2.822
|
| 引用数 |
16
|
|
WOS 分野
|
VETERINARY SCIENCES
MYCOLOGY
INFECTIOUS DISEASES
|
| リソース情報 |
| 病原微生物 |
IFM 5415
IFM 5418
IFM 40752
IFM 41329
IFM 41330
IFM 41332
IFM 41333
IFM 41334
IFM 41335
IFM 41612
IFM 41659
IFM 47750
IFM 49109
IFM 50248
IFM 50249
IFM 50954
IFM 52673
IFM 52674
IFM 52675
IFM 52676
IFM 52677
IFM 52876
IFM 52877
IFM 54223
IFM 54224
IFM 54225
IFM 54226
IFM 54227 |
