RRC ID 31741
Author Suh MK, Lim JW, Lee YH, Ha GY, Kim H, Kim JR, Yaguchi T, Nishimura K.
Title Subcutaneous hyalohyphomycosis due to Cephalotheca foveolata in an immunocompetent host.
Journal Br J Dermatol
Abstract We report the first case of subcutaneous hyalohyphomycosis caused by the genus Cephalotheca, which has not been reported to cause human infection. A 67-year-old immunocompetent farmer presented with a 10-year history of verrucous erythematous plaques on the right foot dorsum, great toe, heel and sole. Histopathology of the lesions revealed chronic granulomatous inflammation with numerous nonpigmented fungal spores in the dermis. Cultures of biopsy specimens on Sabouraud's dextrose agar for 2 weeks developed into yellowish brown, velvety colonies that subsequently turned black after 8 weeks because of the production of black cleistothecia indicating the teleomorph. On the basis of mycological features, scanning electron microscopic morphology and molecular analysis data, a new species of Cephalotheca was identified and designated Cephalotheca foveolata. Because there was no response to the antifungal agents administered, the patient was successfully treated by surgical excision with skin graft.
Volume 154(6)
Pages 1184-9
Published 2006-6-1
DOI 10.1111/j.1365-2133.2006.07158.x
PMID 16704653
MeSH Aged Ascomycota / classification* Dermatomycoses / microbiology* Dermatomycoses / pathology Dermatomycoses / surgery Foot Dermatoses / microbiology* Foot Dermatoses / pathology Foot Dermatoses / surgery Humans Immunocompetence Male Microscopy, Electron, Scanning Spores, Fungal / isolation & purification
IF 7.0
Times Cited 6
Pathogenic microorganisms IFM 50359 IFM 51305 IFM 52863 IFM 52879 IFM 52883 IFM 52886 IFM 52901 IFM 52905 IFM 52906 IFM 52940 IFM 52941 IFM 53377 IFM 53859 IFM 53860 IFM 53861 IFM 53862 IFM 53864