Reference - Detail
| RRC ID | 31756 |
|---|---|
| Author | Nozawa K, Horie Y, Udagawa S, Kawai K, Yamazaki M. |
| Title | Isolation of a new tremorgenic indoloditerpene, 1'-O-acetylpaxilline, from Emericella striata and distribution of paxilline in Emericella spp. |
| Journal | Chem Pharm Bull (Tokyo) |
| Abstract |
The distribution of a tremorgenic mycotoxin, paxilline (1), was investigated in 19 species belonging to the genus Emericella. It was found that Emericella desertorum, E. foveolata, and E. striata produced paxilline (1). A new type of indoloditerpene, emindole DA (4), was also found in E. quadrilineata. A new tremorgenic indoloditerpene, 1'-O-acetylpaxilline (3), was isolated from the mycelium of E. striata. Its structure was established on the basis of spectroscopic investigations. |
| Volume | 37(5) |
| Pages | 1387-9 |
| Published | 1989-5-1 |
| DOI | 10.1248/cpb.37.1387 |
| PMID | 2630106 |
| MeSH | Acetylation Animals Ascomycota / analysis Ascomycota / metabolism* Chemical Phenomena Chemistry Diterpenes / analysis Diterpenes / isolation & purification* Diterpenes / pharmacology Indoles / analysis Indoles / isolation & purification* Indoles / metabolism* Indoles / pharmacology Mice Tremor / chemically induced* |
| IF | 1.416 |
| Times Cited | 13 |
| WOS Category | CHEMISTRY, MEDICINAL CHEMISTRY, MULTIDISCIPLINARY PHARMACOLOGY & PHARMACY |
| Resource | |
| Pathogenic microorganisms | IFM 4521 IFM 42003 IFM 42004 IFM 42005 IFM 42006 IFM 42010 IFM 42011 IFM 42012 IFM 42015 IFM 42016 IFM 42017 IFM 42020 IFM 42021 IFM 42024 |