Reference - Detail
| RRC ID | 31758 |
|---|---|
| Author | Hirano K, Kubota T, Tsuda M, Mikami Y, Kobayashi J. |
| Title | Pyrinodemins B-D, potent cytotoxic bis-pyridine alkaloids from marine sponge amphimedon sp. |
| Journal | Chem Pharm Bull (Tokyo) |
| Abstract |
New bis-pyridine alkaloids, pyrinodemins B-D (1-3), have been isolated together with pyrinodemin A (4) and related 3-alkyl pyridine alkaloids 5-8 from the Okinawan marine sponge Amphimedon sp. and the structures were elucidated from spectroscopic data. Pyrinodemins B-D (1-3) showed potent cytotoxicity, while compounds 5-8 exhibited antimicrobial activity. |
| Volume | 48(7) |
| Pages | 974-7 |
| Published | 2000-7-1 |
| DOI | 10.1248/cpb.48.974 |
| PMID | 10923825 |
| MeSH | Alkaloids / chemistry Alkaloids / isolation & purification* Alkaloids / pharmacology Animals Anti-Bacterial Agents Anti-Infective Agents / chemistry Anti-Infective Agents / isolation & purification* Anti-Infective Agents / pharmacology Bacteria / drug effects Candida albicans / drug effects Porifera / chemistry* Pyridines / chemistry Pyridines / isolation & purification Pyridines / pharmacology |
| IF | 1.416 |
| Times Cited | 46 |
| WOS Category | CHEMISTRY, MULTIDISCIPLINARY CHEMISTRY, MEDICINAL PHARMACOLOGY & PHARMACY |
| Altmetric score |
オルトメトリクス指標項目
|
| The most frequently cited source | Patent(IFI CLAIMS) |
| Total number of mentions | 2 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Pathogenic microorganisms | IFM 2057 IFM 40213 IFM 40215 |