RRC ID 31769
Author Kamei K, Unno H, Nagao K, Kuriyama T, Nishimura K, Miyaji M.
Title Allergic bronchopulmonary mycosis caused by the basidiomycetous fungus Schizophyllum commune.
Journal Clin Infect Dis
Abstract We describe, to our knowledge, the first case of allergic bronchopulmonary mycosis (ABPM) caused by the basidiomycetous fungus Schizophyllum commune in an otherwise healthy woman. Bronchoscopic analysis repeatedly disclosed S. commune hyphae in the bronchi of the lingular lobe; these hyphae were originally misidentified as Aspergillus because the presence of clamp connections was overlooked. A lingular infiltrate with ectatic proximal bronchi, eosinophilia, an elevated serum level of IgE, and antibodies to S. commune supported the diagnosis. It is sometimes difficult to isolate and identify S. commune in clinical specimens, and hence only a limited number of cases of ABPM might have been correctly diagnosed in the past. We suspect, therefore, that some cases of ABPM caused by an allergic reaction to S. commune may be misdiagnosed as allergic bronchopulmonary aspergillosis or eosinophilic pneumonia of unknown origin. The significance of S. commune in allergic bronchopulmonary diseases is discussed.
Volume 18(3)
Pages 305-9
Published 1994-3-1
DOI 10.1093/clinids/18.3.305
PMID 8011808
MeSH Antibodies, Fungal / blood Antigens, Fungal / isolation & purification Bronchoalveolar Lavage Fluid / microbiology Enzyme-Linked Immunosorbent Assay Female Humans Hypersensitivity / diagnosis Hypersensitivity / etiology* Hypersensitivity / microbiology Lung Diseases, Fungal / diagnosis Lung Diseases, Fungal / etiology* Lung Diseases, Fungal / microbiology Middle Aged Schizophyllum / immunology Schizophyllum / isolation & purification Schizophyllum / pathogenicity*
IF 8.313
Times Cited 71
Pathogenic microorganisms IFM 41942