RRC ID 31770
Author Amitani R, Nishimura K, Niimi A, Kobayashi H, Nawada R, Murayama T, Taguchi H, Kuze F.
Title Bronchial mucoid impaction due to the monokaryotic mycelium of Schizophyllum commune.
Journal Clin Infect Dis
Abstract We report, to our knowledge, the first case of mucoid impaction of the bronchi due to a hypersensitivity reaction to the monokaryotic mycelium of Schizophyllum commune. The patient was hospitalized because of mild asthma attacks, persistent cough, peripheral eosinophilia, and "gloved finger" shadows on a chest roentgenogram. Bronchoscopic examination disclosed mucoid impactions that consisted of accumulations of eosinophils, Charcot-Leyden crystals, and nondichotomously branched hyphae in B3, B9, and B10 of the left lung. Cultures of the mucous plugs and sputum samples yielded white, felt-like mycelial colonies that were later identified as the monokaryotic mycelium of S. commune by use of mating tests with established monokaryotic and dikaryotic strains of S. commune. The results of tests for serum antibody to S. commune cytosol antigen were positive. Repeated bronchoscopies for performing bronchial toilet were effective in removing the mucous plugs and relieving the patient's symptoms. We suggest that the monokaryotic mycelium of S. commune should be considered as one of the fungi that can cause hypersensitivity-related lung diseases.
Volume 22(1)
Pages 146-8
Published 1996-1-1
DOI 10.1093/clinids/22.1.146
PMID 8824983
MeSH Aged Bronchi / immunology Bronchi / pathology Bronchial Hyperreactivity / immunology* Bronchial Hyperreactivity / microbiology Bronchial Hyperreactivity / pathology Female Follow-Up Studies Humans Lung / immunology Lung / pathology Mucus* Schizophyllum / immunology* Schizophyllum / isolation & purification Tomography Scanners, X-Ray Computed
IF 9.055
Times Cited 32
WOS Category INFECTIOUS DISEASES IMMUNOLOGY MICROBIOLOGY
Resource
Pathogenic microorganisms IFM 46097 IFM 46098 IFM 46099 IFM 46100 IFM 46101 IFM 46102 IFM 46103 IFM 46578 IFM 46581 IFM 46800