| RRC ID |
3182
|
| 著者 |
Yaguchi T, Takizawa K, Taguchi H, Tanaka R, Kubota T, Kubota Y, Kubota M, Fukushima K.
|
| タイトル |
[Antifungal activity of the novel adduct, GX-95, of silver with nanometer-scale particles to peptidic hydrolysates from collagen].
|
| ジャーナル |
Nihon Ishinkin Gakkai Zasshi
|
| Abstract |
Silver has long been known to have an antimicrobial activity against bacteria and other microorganisms, and has been used as eating utensils, as dental fillings and so on. We developed a novel adduct, GX-95, of silver with nanometer-scale particles to peptidic hydrolysates from collagen. Antifungal activity of the adduct against pathogenic yeasts and filamentous fungi was examined in terms of minimal inhibitory concentrations (MICs). GX-95 was found to possess strong and broad antifungal activities against all fungi examined in the following MICs: 0.25 to 0.31 microg/ml for Candida albicans including resistant strains to fluconazole, itraconazole and flucytosine, 0.05 to 0.2 microg/ml for Cryptococcus neoformans strains, 0.025 to 0.4 microg/ml for Aspergillus fumigatus strains, 0.4 microg/ml for Trichophyton rubrum, and 0.05 microg/ml for Cladophialophora carrionii.
|
| 巻・号 |
48(2)
|
| ページ |
97-100
|
| 公開日 |
2007-1-1
|
| DOI |
10.3314/jjmm.48.97
|
| PMID |
17502845
|
| MeSH |
Antifungal Agents / pharmacology*
Collagen
Fungi / drug effects*
Nanoparticles
Protein Hydrolysates
Silver / pharmacology*
|
| リソース情報 |
| 病原微生物 |
IFM 4802
IFM 5746
IFM 5771
IFM 5777
IFM 5801
IFM 40018
IFM 40210
IFM 40217
IFM 40951
IFM 41348
IFM 41362
IFM 41398
IFM 41818
IFM 41881
IFM 41935
IFM 45108
IFM 45802
IFM 46816
IFM 46843
IFM 46888
IFM 46907
IFM 46908
IFM 46910
IFM 47078
IFM 48429
IFM 51756
IFM 54354 |
