Reference - Detail
| RRC ID | 31856 |
|---|---|
| Author | Tanaka Y, Komaki H, Yazawa K, Mikami Y, Nemoto A, Tojyo T, Kadowaki K, Shigemori H, Kobayashi J. |
| Title | Brasilinolide A, a new macrolide antibiotic produced by Nocardia brasiliensis: producing strain, isolation and biological activity. |
| Journal | J Antibiot (Tokyo) |
| Abstract |
A new 32-membered macrolide antibiotic, brasilinolide A was isolated from the fermentation broth of Nocardia sp. IFM 0406. The producer was identified as Nocardia brasiliensis. The antibiotic was only active against Aspergillus niger, but not active against other fungi including yeasts as well as other filamentous like fungi and bacteria. Brasilinolide A exerted an immunosuppressive activity in the assay system of a mixed lymphocyte reaction (MLR). |
| Volume | 50(12) |
| Pages | 1036-41 |
| Published | 1997-12-1 |
| DOI | 10.7164/antibiotics.50.1036 |
| PMID | 9510911 |
| MeSH | Animals Anti-Bacterial Agents / biosynthesis Anti-Bacterial Agents / chemistry Anti-Bacterial Agents / isolation & purification* Anti-Bacterial Agents / pharmacology Bacteria / drug effects Cells, Cultured / drug effects Culture Media Fungi / drug effects HeLa Cells / drug effects Humans Macrolides / chemistry* Macrolides / isolation & purification* Macrolides / pharmacology Mice Mice, Inbred BALB C Mice, Inbred C57BL Nocardia / chemistry* Nocardia / classification |
| IF | 2.668 |
| Times Cited | 45 |
| WOS Category | PHARMACOLOGY & PHARMACY BIOTECHNOLOGY & APPLIED MICROBIOLOGY IMMUNOLOGY MICROBIOLOGY |
| Altmetric score |
オルトメトリクス指標項目
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| Total number of mentions | 0 |
| Resource | |
| Pathogenic microorganisms | IFM 40081 IFM 41994 IFM 40606 IFM 0236 IFM 0333 IFM 0406 |