Reference - Detail
|Author||Maeda A, Yazawa K, Mikami Y, Ishibashi M, Kobayashi J.|
|Title||The producer and biological activities of SO-75R1, a new mutactimycin group antibiotic [corrected].|
|Journal||J Antibiot (Tokyo)|
The producer of SO-75R1, a new anthracycline group antibiotic was identified as Nocardia brasiliensis. SO-75R1 was active against Gram-positive bacteria, but not active against Gram-negative bacteria or fungi. All tested Nocardia brasiliensis strains as well as the producer itself were resistant to SO-75R1, although four other pathogenic Nocardia, i.e. N. asteroides, N. nova, N. farcinica and N. otitidiscaviarum were sensitive [corrected].
|MeSH||Animals Anthracyclines* Antibiotics, Antineoplastic / chemistry Antibiotics, Antineoplastic / isolation & purification Antibiotics, Antineoplastic / pharmacology* Drug Screening Assays, Antitumor Fungi / drug effects Gram-Negative Bacteria / drug effects Gram-Positive Bacteria / drug effects* Leukemia L1210 / drug therapy Male Mice Microbial Sensitivity Tests Microbiological Techniques Nocardia / chemistry* Tumor Cells, Cultured Vero Cells / drug effects|
|WOS Category||PHARMACOLOGY & PHARMACY BIOTECHNOLOGY & APPLIED MICROBIOLOGY IMMUNOLOGY MICROBIOLOGY|
|Pathogenic microorganisms||IFM 0075 IFM 0229 IFM 0234 IFM 0236 IFM 0239 IFM 0253 IFM 0256 IFM 0273 IFM 0274 IFM 0275 IFM 0279 IFM 0280 IFM 0281 IFM 0284 IFM 0290 IFM 0294 IFM 0301 IFM 0319 IFM 0320 IFM 0337 IFM 0342 IFM 0348 IFM 0349 IFM 0354 IFM 0356 IFM 0362 IFM 40038 IFM 40606 IFM 40615|