Reference - Detail
| RRC ID | 31927 |
|---|---|
| Author | Nakadate S, Nozawa K, Sato H, Horie H, Fujii Y, Nagai M, Hosoe T, Kawai K, Yaguchi T. |
| Title | Antifungal cyclic depsipeptide, eujavanicin A, isolated from Eupenicillium javanicum. |
| Journal | J Nat Prod |
| Abstract |
In the course of searching for new antifungal agents, a new cyclic depsipeptide, eujavanicin A (1), was isolated from Eupenicillium javanicum as an antifungal agent against the human pathogenic filamentous fungus Aspergillus fumigatus. The structure of 1 was established by spectroscopic and chemical investigations. The absolute stereochemistry was elucidated by Marfey's method and by chiral HPLC analysis. |
| Volume | 71(9) |
| Pages | 1640-2 |
| Published | 2008-9-1 |
| DOI | 10.1021/np8002904 |
| PMID | 18771240 |
| MeSH | Antifungal Agents / chemistry Antifungal Agents / isolation & purification* Antifungal Agents / pharmacology* Aspergillus fumigatus / drug effects* Bacillus subtilis / drug effects Depsipeptides / chemistry Depsipeptides / isolation & purification* Depsipeptides / pharmacology* Escherichia coli / drug effects Humans Japan Microbial Sensitivity Tests Molecular Structure Salmonella enteritidis / drug effects Staphylococcus aureus / drug effects |
| IF | 3.782 |
| Times Cited | 12 |
| WOS Category | PLANT SCIENCES PHARMACOLOGY & PHARMACY CHEMISTRY, MEDICINAL |
| Resource | |
| Pathogenic microorganisms | IFM 54704 |