| RRC ID |
31929
|
| 著者 |
Shigemori H, Komaki H, Yazawa K, Mikami Y, Nemoto A, Tanaka Y, Sasaki T, In Y, Ishida T, Kobayashi J.
|
| タイトル |
Brasilicardin A. A Novel Tricyclic Metabolite with Potent Immunosuppressive Activity from Actinomycete Nocardiabrasiliensis.
|
| ジャーナル |
J Org Chem
|
| Abstract |
A novel tricyclic metabolite, brasilicardin A (1), with potent immunosuppressive activity has been isolated from the cultured broth of the actinomycete Nocardia brasiliensis IFM 0406, and the structure including absolute stereochemistry was established on the basis of spectroscopic data, chemical means, and X-ray analysis. Brasilicardin A (1) is the first tricyclic compound consisting of an anti/syn/anti-perhydrophenanthrene skeleton with a rhamnose, an N-acetylglucosamine, and an amino acid moiety.
|
| 巻・号 |
63(20)
|
| ページ |
6900-6904
|
| 公開日 |
1998-10-2
|
| DOI |
10.1021/jo9807114
|
| PII |
jo9807114
|
| PMID |
11672311
|
| IF |
4.335
|
| 引用数 |
55
|
| リソース情報 |
| 病原微生物 |
IFM 0075
IFM 0089
IFM 0406 |
