| RRC ID |
32206
|
| Author |
Kobayashi H, Sano A, Aragane N, Fukuoka M, Tanaka M, Kawaura F, Fukuno Y, Matsuishi E, Hayashi S.
|
| Title |
Disseminated infection by Bipolaris spicifera in an immunocompetent subject.
|
| Journal |
Med Mycol
|
| Abstract |
We report a case of disseminated infection due to Bipolaris spicifera in an immunocompetent male. Histopathological studies of lymph node, lung, and liver biopsy specimens showed a dark pigmented, granular fungal structure inside the granuloma. The disease was accompanied by the unusual feature of positive lupus anticoagulant in serum and low-density areas expanding along the portal vein in the liver. The disease responded to combination therapy with intravenous amphotericin B and voriconazole, but recurred during oral itraconazole. The fungal isolate from the lymph node was identified as Bipolaris spicifera on the basis of morphology and molecular biological data.
|
| Volume |
46(4)
|
| Pages |
361-5
|
| Published |
2008-6-1
|
| DOI |
10.1080/13693780701883490
|
| PII |
791510451
|
| PMID |
18415844
|
| MeSH |
Adult
Amphotericin B / therapeutic use
Ascomycota / cytology
Ascomycota / isolation & purification*
DNA, Fungal / analysis
DNA, Ribosomal / analysis
Humans
Immunocompetence
Itraconazole / therapeutic use
Lymph Nodes / microbiology
Male
Mycoses / drug therapy
Mycoses / immunology
Mycoses / pathology*
Pyrimidines / therapeutic use
Sequence Analysis, DNA
Triazoles / therapeutic use
Voriconazole
|
| IF |
2.822
|
| Times Cited |
17
|
|
WOS Category
|
VETERINARY SCIENCES
MYCOLOGY
INFECTIOUS DISEASES
|
| Resource |
| Pathogenic microorganisms |
IFM 41459
IFM 41460
IFM 41474
IFM 52187
IFM 52973
IFM 55164 |
