Reference - Detail
| RRC ID | 32227 |
|---|---|
| Author | Tanaka Y, Yazawa K, Dabbs ER, Nishikawa K, Komaki H, Mikami Y, Miyaji M, Morisaki N, Iwasaki S. |
| Title | Different rifampicin inactivation mechanisms in Nocardia and related taxa. |
| Journal | Microbiol Immunol |
| Abstract |
Mycolic acid-containing bacteria inactivate rifampicin in a variety of ways such as glucosylation, ribosylation, phosphorylation and decolorization. These inactivations were found to be a species-specific phenomena in Nocardia and related taxa. Gordona, Tsukamurella and fast-growing Mycobacterium modified rifampicin by ribosylation of the 23-OH group of the antibiotic. Such ribosylation was not observed in Rhodococcus and Corynebacterium, but phosphorylation of the 21-OH group of rifampicin was observed in one strain of Rhodococcus. Nocardia modified the antibiotic by glucosylation (23-OH group) and phosphorylation, but ribosylation was not observed. |
| Volume | 40(1) |
| Pages | 1-4 |
| Published | 1996-1-1 |
| DOI | 10.1111/j.1348-0421.1996.tb03303.x |
| PMID | 8871521 |
| MeSH | Actinomycetales / drug effects* Actinomycetales / metabolism Drug Resistance, Microbial Glycosylation Microbial Sensitivity Tests Phosphorylation Rifampin / chemistry Rifampin / pharmacology* Species Specificity |
| IF | 1.566 |
| Times Cited | 28 |
| WOS Category | IMMUNOLOGY MICROBIOLOGY |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | Wikipedia |
| Total number of mentions | 1 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Pathogenic microorganisms | IFM 0025 IFM 0132 IFM 0147 IFM 0149 IFM 0150 IFM 0161 IFM 0162 IFM 0259 IFM 0359 IFM 0405 IFM 0413 IFM 0414 IFM 0433 IFM 0451 IFM 0452 IFM 0453 IFM 0454 IFM 0473 IFM 0474 IFM 0475 IFM 0476 IFM 0477 IFM 0478 IFM 0479 IFM 2057 |