RRC ID 32262
著者 Iwatsu T, Miyaji M, Taguchi H, Okamoto S, Kurita N.
タイトル Skin test-active substance prepared from culture filtrate of Fonsecaea pedrosoi.
ジャーナル Mycopathologia
Abstract Ethanol-precipitated substance (EP) was prepared from culture filtrate of Fonsecaea pedrosoi. EP was separated into two components by passing through a Sephadex G-50 column; the faster passing component was referred to as EP-1, the slower as EP-2. EP-1 and EP-2 were evaluated as an antigen for detecting cutaneous delayed hypersensitivity in patients with chromomycosis. EP-1 elicited positive delayed skin reactions in all of 8 patients with chromomycosis, of which 7 caused by F. pedrosoi and one by Exophiala jeunselmei. Healthy subjects, patients with sporotrichosis and patients with tinea barbae failed to react to EP-1. These results indicate that EP-1 is a useful tool for detecting cutaneous delayed hypersensitivity in patients with chromomycosis caused by F. pedrosoi. It was found that precipitin test using EP-1 as an antigen had little diagnostic value in chromomycosis. EP-2 did not show antigenic activity in both skin and precipitin reactions.
巻・号 67(2)
ページ 101-5
公開日 1979-5-31
DOI 10.1007/BF00440680
PMID 573371
MeSH Adult Aged Antigens, Fungal / immunology* Chromoblastomycosis / diagnosis* Diagnosis, Differential Female Humans Hypersensitivity, Delayed / immunology* Male Middle Aged Mitosporic Fungi / immunology* Precipitin Tests Skin Tests
IF 2.452
リソース情報
病原微生物 IFM 46378