RRC ID |
32262
|
著者 |
Iwatsu T, Miyaji M, Taguchi H, Okamoto S, Kurita N.
|
タイトル |
Skin test-active substance prepared from culture filtrate of Fonsecaea pedrosoi.
|
ジャーナル |
Mycopathologia
|
Abstract |
Ethanol-precipitated substance (EP) was prepared from culture filtrate of Fonsecaea pedrosoi. EP was separated into two components by passing through a Sephadex G-50 column; the faster passing component was referred to as EP-1, the slower as EP-2. EP-1 and EP-2 were evaluated as an antigen for detecting cutaneous delayed hypersensitivity in patients with chromomycosis. EP-1 elicited positive delayed skin reactions in all of 8 patients with chromomycosis, of which 7 caused by F. pedrosoi and one by Exophiala jeunselmei. Healthy subjects, patients with sporotrichosis and patients with tinea barbae failed to react to EP-1. These results indicate that EP-1 is a useful tool for detecting cutaneous delayed hypersensitivity in patients with chromomycosis caused by F. pedrosoi. It was found that precipitin test using EP-1 as an antigen had little diagnostic value in chromomycosis. EP-2 did not show antigenic activity in both skin and precipitin reactions.
|
巻・号 |
67(2)
|
ページ |
101-5
|
公開日 |
1979-5-31
|
DOI |
10.1007/BF00440680
|
PMID |
573371
|
MeSH |
Adult
Aged
Antigens, Fungal / immunology*
Chromoblastomycosis / diagnosis*
Diagnosis, Differential
Female
Humans
Hypersensitivity, Delayed / immunology*
Male
Middle Aged
Mitosporic Fungi / immunology*
Precipitin Tests
Skin Tests
|
IF |
2.452
|
リソース情報 |
病原微生物 |
IFM 46378 |