RRC ID 32626
Author Hosoe T, Nozawa K, Kawahara N, Fukushima K, Nishimura K, Miyaji M, Kawai K.
Title Isolation of a new potent cytotoxic pigment along with indigotin from the pathogenic basidiomycetous fungus Schizophyllum commune.
Journal Mycopathologia
Abstract An indole derivative, schizocommunin, was isolated along with indigotin (indigo), indirubin, isatin, and tryptanthrin, from the liquid culture medium in which a culture of Schizophyllum commune, isolated from the bronchus of a human patient with allergic bronchopulmonary mycosis, had been grown. The structure of schizocommunin was established by spectroscopic investigation. Schizocommunin showed the strong cytotoxicity against murine lymphoma cells. The assignments of the 1H- and 13C-NMR signals of indigotin were also listed.
Volume 146(1)
Pages 9-12
Published 1999-1-1
DOI 10.1023/a:1007082619328
PMID 10721515
MeSH Animals Antineoplastic Agents / isolation & purification* Indigo Carmine Indoles / isolation & purification* Indoles / toxicity Lymphoma Mice Nuclear Magnetic Resonance, Biomolecular Pigments, Biological / isolation & purification Schizophyllum / chemistry* Tumor Cells, Cultured
IF 2.452
Times Cited 31
WOS Category MYCOLOGY
Resource
Pathogenic microorganisms IFM 46788