RRC ID 32630
著者 Sano A, Defaveri J, Tanaka R, Yokoyama K, Kurita N, Franco M, Coelho KI, Bagagli E, Montenegro MR, Miyaji M, Nishimura K.
タイトル Pathogenicities and GP43kDa gene of three Paracoccidioides brasiliensis isolates originated from a nine-banded armadillo (Dasypus novemcinctus).
ジャーナル Mycopathologia
Abstract We studied three different isolates of Paracoccidioides brasiliensis obtained from the mesenteric lymph node (D3LY1), the spleen (D3S1) and the liver (D3LIV1) of the same armadillo (Dasypus novemcinctus). Pulmonal inflammatory area was evaluated by intravenous inoculation of 10(6) yeast cells of each isolates in young, male, ddY mice. Moreover, the partial sequence of GP43kDa gene of P. brasiliensis was analyzed. The lung inflammatory area was greater in animals inoculated with isolate D3S1. The partial sequence of GP43kDa gene indicated that isolate D3S1 is different from isolates D3LY1 and D3LIV1. This study suggested that the same armadillo might be susceptible to multiple P. brasiliensis isolates simultaneously.
巻・号 144(2)
ページ 61-5
公開日 1998-1-1
DOI 10.1023/a:1007024923042
PMID 10481285
MeSH Animals Antigens, Fungal* Armadillos / microbiology* Base Sequence Fungal Proteins / genetics* Glycoproteins* Liver / microbiology Lung Diseases, Fungal / microbiology Lung Diseases, Fungal / pathology Lymph Nodes / microbiology Male Mesentery Mice Molecular Sequence Data Paracoccidioides* / genetics Paracoccidioides* / pathogenicity Paracoccidioidomycosis / microbiology Paracoccidioidomycosis / pathology Polymerase Chain Reaction Soil Microbiology* Specific Pathogen-Free Organisms Spleen / microbiology Water Microbiology*
IF 2.452
引用数 18
WOS 分野 MYCOLOGY
リソース情報
病原微生物 IFM 47195 IFM 47207 IFM 47213