RRC ID 32643
Author Iwasawa MT, Togawa Y, Kamada N, Kambe N, Matsue H, Yazawa K, Yaguchi T, Mikami Y.
Title Lymphocutaneous type of nocardiosis caused by Nocardia vinacea in a patient with polymyositis.
Journal Mycopathologia
Abstract We report a lymphocutaneous type of nocardiosis caused by Nocardia vinacea. A 62-year-old woman with polymyositis presented with some erythematous swellings and subcutaneous abscesses on her right middle finger and the dorsum of her hand, which had persisted for 2 weeks. Culturing of the excised nodule and pus revealed orange to orange-tan colonies with scanty whitish aerial mycelia. The isolate was identified as N. vinacea on the basis of its biochemical and chemotaxonomic characteristics and the results of molecular biological analysis. In our case, oral minocycline (MINO) and trimethoprim-sulfamethoxazole (TMP-SMX) for 7 weeks did not improve the clinical manifestation, even though in vitro susceptibility testing of the isolate predicted its susceptibility to MINO and TMP-SMX. Treatment with partial surgical excision followed by TMP-SMX and meropenem administration was effective. This is the first reported case of a lymphocutaneous type of nocardiosis caused by N. vinacea.
Volume 172(1)
Pages 47-53
Published 2011-7
DOI 10.1007/s11046-011-9391-0
PMID 21264517
MeSH Anti-Bacterial Agents / administration & dosage Bacterial Typing Techniques DNA, Bacterial / chemistry DNA, Bacterial / genetics DNA, Ribosomal / chemistry DNA, Ribosomal / genetics Debridement Female Humans Minocycline / administration & dosage Nocardia / classification Nocardia / genetics Nocardia / isolation & purification* Nocardia / physiology Nocardia Infections / diagnosis* Nocardia Infections / microbiology* Nocardia Infections / pathology Nocardia Infections / therapy Polymyositis / complications* RNA, Ribosomal, 16S / genetics Sequence Analysis, DNA Skin Diseases, Bacterial / diagnosis Skin Diseases, Bacterial / microbiology Skin Diseases, Bacterial / pathology Skin Diseases, Bacterial / therapy Thienamycins / administration & dosage Treatment Outcome Trimethoprim, Sulfamethoxazole Drug Combination / administration & dosage
IF 1.476
Times Cited 1
WOS Category MYCOLOGY
Resource
Pathogenic microorganisms IFM 0092 IFM 0236 IFM 0265 IFM 0283 IFM 0286 IFM 0290 IFM 0319 IFM 0323 IFM 0333 IFM 0372 IFM 0391 IFM 0475 IFM 0575 IFM 0624 IFM 0784 IFM 0833 IFM 0851 IFM 0856 IFM 0937 IFM 10001 IFM 10029 IFM 10035 IFM 10084 IFM 10086 IFM 10088 IFM 10138 IFM 10145 IFM 10147 IFM 10173 IFM 10174 IFM 10175 IFM 10176 IFM 10177 IFM 10235 IFM 10284 IFM 10331 IFM 10344 IFM 10366 IFM 10376 IFM 10533 IFM 10549 IFM 10560 IFM 10564 IFM 10565 IFM 10572 IFM 10588 IFM 10589 IFM 10635 IFM 10710 IFM 10838