RRC ID |
32643
|
著者 |
Iwasawa MT, Togawa Y, Kamada N, Kambe N, Matsue H, Yazawa K, Yaguchi T, Mikami Y.
|
タイトル |
Lymphocutaneous type of nocardiosis caused by Nocardia vinacea in a patient with polymyositis.
|
ジャーナル |
Mycopathologia
|
Abstract |
We report a lymphocutaneous type of nocardiosis caused by Nocardia vinacea. A 62-year-old woman with polymyositis presented with some erythematous swellings and subcutaneous abscesses on her right middle finger and the dorsum of her hand, which had persisted for 2 weeks. Culturing of the excised nodule and pus revealed orange to orange-tan colonies with scanty whitish aerial mycelia. The isolate was identified as N. vinacea on the basis of its biochemical and chemotaxonomic characteristics and the results of molecular biological analysis. In our case, oral minocycline (MINO) and trimethoprim-sulfamethoxazole (TMP-SMX) for 7 weeks did not improve the clinical manifestation, even though in vitro susceptibility testing of the isolate predicted its susceptibility to MINO and TMP-SMX. Treatment with partial surgical excision followed by TMP-SMX and meropenem administration was effective. This is the first reported case of a lymphocutaneous type of nocardiosis caused by N. vinacea.
|
巻・号 |
172(1)
|
ページ |
47-53
|
公開日 |
2011-7-1
|
DOI |
10.1007/s11046-011-9391-0
|
PMID |
21264517
|
MeSH |
Anti-Bacterial Agents / administration & dosage
Bacterial Typing Techniques
DNA, Bacterial / chemistry
DNA, Bacterial / genetics
DNA, Ribosomal / chemistry
DNA, Ribosomal / genetics
Debridement
Female
Humans
Meropenem
Minocycline / administration & dosage
Nocardia / classification
Nocardia / genetics
Nocardia / isolation & purification*
Nocardia / physiology
Nocardia Infections / diagnosis*
Nocardia Infections / microbiology*
Nocardia Infections / pathology
Nocardia Infections / therapy
Polymyositis / complications*
RNA, Ribosomal, 16S / genetics
Sequence Analysis, DNA
Skin Diseases, Bacterial / diagnosis
Skin Diseases, Bacterial / microbiology
Skin Diseases, Bacterial / pathology
Skin Diseases, Bacterial / therapy
Thienamycins / administration & dosage
Treatment Outcome
Trimethoprim, Sulfamethoxazole Drug Combination / administration & dosage
|
IF |
2.452
|
引用数 |
3
|
WOS 分野
|
MYCOLOGY
|
リソース情報 |
病原微生物 |
IFM 0092
IFM 0236
IFM 0265
IFM 0283
IFM 0286
IFM 0290
IFM 0319
IFM 0323
IFM 0333
IFM 0372
IFM 0391
IFM 0475
IFM 0575
IFM 0624
IFM 0784
IFM 0833
IFM 0851
IFM 0856
IFM 0937
IFM 10001
IFM 10029
IFM 10035
IFM 10084
IFM 10086
IFM 10088
IFM 10138
IFM 10145
IFM 10147
IFM 10173
IFM 10174
IFM 10175
IFM 10176
IFM 10177
IFM 10235
IFM 10284
IFM 10331
IFM 10344
IFM 10366
IFM 10376
IFM 10533
IFM 10549
IFM 10560
IFM 10564
IFM 10565
IFM 10572
IFM 10588
IFM 10589
IFM 10635
IFM 10710
IFM 10838 |