Reference - Detail
| RRC ID | 3343 |
|---|---|
| Author | Weiss B. |
| Title | YjjG, a dUMP phosphatase, is critical for thymine utilization by Escherichia coli K-12. |
| Journal | J Bacteriol |
| Abstract |
Exogenous thymine must be converted to thymidine to enable a thyA (thymidylate synthase) mutant to grow. The deoxyribose in the thymidine comes from dUMP, which must first be dephosphorylated. The nucleotidase YjjG is critical for this step. A yjjG thyA mutant cannot use thymine for growth on a glucose minimal medium. |
| Volume | 189(5) |
| Pages | 2186-9 |
| Published | 2007-3-1 |
| DOI | 10.1128/JB.01645-06 |
| PII | JB.01645-06 |
| PMID | 17189366 |
| PMC | PMC1855703 |
| MeSH | Deoxyuracil Nucleotides / metabolism* Escherichia coli / metabolism* Escherichia coli Proteins / physiology* N-Glycosyl Hydrolases / physiology* Phosphorylation Thymidylate Synthase / physiology Thymine / metabolism* |
| IF | 3.006 |
| Times Cited | 12 |
| WOS Category | MICROBIOLOGY |
| Resource | |
| Prokaryotes E. coli | |