Reference - Detail
RRC ID | 3343 |
---|---|
Author | Weiss B. |
Title | YjjG, a dUMP phosphatase, is critical for thymine utilization by Escherichia coli K-12. |
Journal | J Bacteriol |
Abstract |
Exogenous thymine must be converted to thymidine to enable a thyA (thymidylate synthase) mutant to grow. The deoxyribose in the thymidine comes from dUMP, which must first be dephosphorylated. The nucleotidase YjjG is critical for this step. A yjjG thyA mutant cannot use thymine for growth on a glucose minimal medium. |
Volume | 189(5) |
Pages | 2186-9 |
Published | 2007-3-1 |
DOI | 10.1128/JB.01645-06 |
PII | JB.01645-06 |
PMID | 17189366 |
PMC | PMC1855703 |
MeSH | Deoxyuracil Nucleotides / metabolism* Escherichia coli / metabolism* Escherichia coli Proteins / physiology* N-Glycosyl Hydrolases / physiology* Phosphorylation Thymidylate Synthase / physiology Thymine / metabolism* |
IF | 3.006 |
Times Cited | 12 |
WOS Category | MICROBIOLOGY |
Resource | |
Prokaryotes E. coli |