Reference - Detail
| RRC ID | 33493 |
|---|---|
| Author | Noma Y, Sideras P, Naito T, Bergstedt-Lindquist S, Azuma C, Severinson E, Tanabe T, Kinashi T, Matsuda F, Yaoita Y. |
| Title | Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter. |
| Journal | Nature |
| Abstract |
Complementary DNA encoding the IgG1 induction factor, the first lymphokine directed to B lymphocytes, from a murine T-cell line has been cloned using a new strategy. The putative primary amino-acid sequence was deduced from the nucleotide sequence determined. The lymphokine synthesized by the direction of this cloned cDNA has many other functions, such as production of B-cell growth factor-1 and induction of Ia on B cells. |
| Volume | 319(6055) |
| Pages | 640-6 |
| Published | 1986-2-20 |
| DOI | 10.1038/319640a0 |
| PMID | 3005865 |
| MeSH | Amino Acid Sequence Animals B-Lymphocytes / immunology* Base Sequence Chromosome Mapping Cloning, Molecular DNA / genetics DNA Restriction Enzymes Genetic Vectors Growth Substances / genetics* Histocompatibility Antigens Class II / analysis Immunoglobulin G / biosynthesis Interleukin-4 Lymphokines / genetics* Mice Promoter Regions, Genetic Protein Biosynthesis RNA, Messenger / genetics T-Lymphocytes / physiology* Xenopus laevis |
| IF | 42.779 |
| WOS Category | MULTIDISCIPLINARY SCIENCES |
| Resource | |
| Prokaryotes E. coli | pSP62-K2 |