論文 - 詳細
| RRC ID | 33585 |
|---|---|
| 著者 | Fujita Y, Freese E. |
| タイトル | Isolation and properties of a Bacillus subtilis mutant unable to produce fructose-bisphosphatase. |
| ジャーナル | J Bacteriol |
| Abstract |
A Bacillus subtilis mutation (gene symbol fdpA1), producing a deficiency of D-fructose-1,6-bisphosphate 1-phosphohydrolase (EC 3.1.3.11, fructose-bisphosphatase), was isolated and genetically purified. An fdpA1-containing mutant did not produce cross-reacting material. It grew on any carbon source that allowed growth of the standard strain except myo-inositol and D-gluconate. Because the mutant could grow on D-fructose, glycerol, or L-malate as the sole carbon source, B. subtilis can produce fructose-6-phosphate and the derived cell wall precursors from these carbon sources in the absence of fructose-bisphosphatase. In other words, during gluconeogenesis B. subtilis must be able to bypass this reaction. Fructose-bisphosphatase is also not needed for the sporulation of B., subtilis. The fdpA1 mutation has the pleiotropic consequence that mutants carrying it cannot produce inositol dehydrogenase (EC 1.1.1.18) and gluconate kinase (EC 2.7.1.12) under conditions that normally induce these enzymes. |
| 巻・号 | 145(2) |
| ページ | 760-7 |
| 公開日 | 1981-2-1 |
| DOI | 10.1128/jb.145.2.760-767.1981 |
| PMID | 6257649 |
| PMC | PMC217176 |
| MeSH | Bacillus subtilis / enzymology Bacillus subtilis / genetics* Carbohydrate Metabolism Cross Reactions Fructose-Bisphosphatase / genetics* Fructose-Bisphosphatase / immunology Gluconates / biosynthesis Gluconates / metabolism Gluconeogenesis Inositol / biosynthesis Inositol / metabolism Phosphotransferases / biosynthesis Phosphotransferases (Alcohol Group Acceptor)* Spores, Bacterial / physiology Sugar Alcohol Dehydrogenases / biosynthesis |
| IF | 3.006 |
| 引用数 | 58 |
| WOS 分野 | MICROBIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | Patent(IFI CLAIMS) |
| 各媒体での言及数の合計 | 4 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 原核生物(枯草菌) | MBS68 MBS75 MBS84 |