論文 - 詳細
| RRC ID | 33590 |
|---|---|
| 著者 | Yoshida K, Sano H, Miwa Y, Ogasawara N, Fujita Y. |
| タイトル | Cloning and nucleotide sequencing of a 15 kb region of the Bacillus subtilis genome containing the iol operon. |
| ジャーナル | Microbiology (Reading) |
| Abstract |
Within the framework of an international project on the sequencing of the whole Bacillus subtilis genome, a 15 kb chromosome segment, which contains the iol operon involved in inositol utilization, has been cloned and sequenced. This region (14,974 bp) contains 12 complete open reading frames (ORFs; genes) and two partial ones; the seventh gene (E83G) is the idh gene encoding inositol dehydrogenase. All the genes identified are transcribed in the same direction as that of the movement of the replication fork. A homology search for their products deduced from the 12 complete ORFs revealed that eight of them exhibit significant homology to known proteins such as fructokinase, acetolactate synthase, fructose-1,6-bisphosphate aldolase (B. subtilis), and PhoB and FtsE proteins (Escherichia coli). It also implied that two genes (B65D and B65E) might encode a set of two-component regulatory proteins and that the B65F gene might encode a protein belonging to the ATP-binding cassette (ABC) family. Based on the features of the nucleotide sequence determined and the results of the homology search, the primary structure of the iol operon is predicted. |
| 巻・号 | 140 ( Pt 9) |
| ページ | 2289-98 |
| 公開日 | 1994-9-1 |
| DOI | 10.1099/13500872-140-9-2289 |
| PMID | 7952181 |
| MeSH | Amino Acid Sequence Bacillus subtilis / genetics* Bacillus subtilis / metabolism Bacterial Proteins / genetics Base Sequence Chromosome Mapping Cloning, Molecular DNA, Bacterial / genetics Genes, Bacterial Genome, Bacterial* Genomic Library Inositol / metabolism Molecular Sequence Data Open Reading Frames Operon Sequence Homology, Amino Acid Sugar Alcohol Dehydrogenases / genetics |
| IF | 2.138 |
| 引用数 | 19 |
| WOS 分野 | MICROBIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | Patent(IFI CLAIMS) |
| 各媒体での言及数の合計 | 9 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 原核生物(枯草菌) | MBS142 |