論文 - 詳細
| RRC ID | 34013 |
|---|---|
| 著者 | Takahata M, Toh H, Nakano A, Takagi M, Murakami M, Ishii Y, Takizawa T, Tanabe S, Morita H. |
| タイトル | Complete sequence analysis of two cryptic plasmids from Bifidobacterium kashiwanohense JCM 15439 (type strain) isolated from healthy infant feces. |
| ジャーナル | Anim Sci J |
| Abstract |
Bifidobacterial plasmids reported so far are derived from a limited number of strains and plasmids of bifidobacterial type strains isolated from humans are unknown. We found that Bifidobacterium kashiwanohense JCM 15439 (type strain) isolated from a healthy infant contained two cryptic plasmids, designated pBBKW-1 and pBBKW-2. We determined and analyzed the complete sequences of both plasmids. pBBKW-1 (7716 bp) was predicted to replicate by a rolling-circle mechanism and encode six protein-coding genes, two of which are putative replication proteins. pBBKW-1 seems to be a cointegrate plasmid containing two copies of the plasmid pMG1 from Bifidobacterium longum. pBBKW-2 (2920 bp) was predicted to encode six protein-coding genes and be a theta-type replicating plasmid, which has been reported to be more stable than a rolling circle-type replicating plasmid frequently found in bifidobacteria. Our finding will provide new insights into safe recombinant plasmid constructions for humans. |
| 巻・号 | 85(2) |
| ページ | 158-63 |
| 公開日 | 2014-2-1 |
| DOI | 10.1111/asj.12095 |
| PMID | 23865717 |
| MeSH | Base Sequence* Bifidobacterium / genetics* Bifidobacterium / isolation & purification Feces / microbiology* Humans Infant Molecular Sequence Data Plasmids / genetics* Sequence Analysis, DNA* |
| IF | 1.399 |
| 引用数 | 3 |
| WOS 分野 | AGRICULTURE, DAIRY & ANIMAL SCIENCE |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 最多言及媒体 | |
| 各媒体での言及数の合計 | 2 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 一般微生物 | JCM 15439 |