RRC ID 34035
Author Odashima Y, Nakamura K, Ikai H, Kanno T, Meirelles L, Sasaki K, Niwano Y.
Title Postantibiotic effect of disinfection treatment by photolysis of hydrogen peroxide.
Journal J Chemother
Abstract The purpose of the present study was to evaluate the postantibiotic effect (PAE) of the disinfection treatment by photolysis of H2O2. Postantibiotic effect was induced in Staphylococcus aureus and Streptococcus salivarius by exposing the bacteria to H2O2 at concentrations of 250-1000 mmol/l, laser irradiation at a wavelength of 405 nm, and the combination of both (photolysis of H2O2) for 10-30 seconds. The photolysis of H2O2 induced significantly longer PAE than other treatments. The PAE was augmented dependently on not only the concentration of H2O2 but the laser irradiation time. Electron spin resonance analysis showed that the hydroxyl radical was also generated dependently on both the concentration of H2O2 and the laser irradiation time, suggesting that the hydroxyl radicals contribute to the PAE. These results suggest that the disinfection treatment by photolysis of H2O2 induces PAE in S. aureus and S. salivarius even though they were treated for only 10-30 seconds.
Volume 26(2)
Pages 92-100
Published 2014-4
DOI 10.1179/1973947813Y.0000000114
PII joc284
PMID 24091288
MeSH Bacteria / drug effects* Disinfection / methods* Hydrogen Peroxide / pharmacology* Photolysis
IF 1.49
Times Cited 2
WOS Category PATHOLOGY PHARMACOLOGY & PHARMACY INFECTIOUS DISEASES ONCOLOGY
Resource
General Microbes JCM 2413 JCM 5707