RRC ID 34035
著者 Odashima Y, Nakamura K, Ikai H, Kanno T, Meirelles L, Sasaki K, Niwano Y.
タイトル Postantibiotic effect of disinfection treatment by photolysis of hydrogen peroxide.
ジャーナル J Chemother
Abstract The purpose of the present study was to evaluate the postantibiotic effect (PAE) of the disinfection treatment by photolysis of H2O2. Postantibiotic effect was induced in Staphylococcus aureus and Streptococcus salivarius by exposing the bacteria to H2O2 at concentrations of 250-1000 mmol/l, laser irradiation at a wavelength of 405 nm, and the combination of both (photolysis of H2O2) for 10-30 seconds. The photolysis of H2O2 induced significantly longer PAE than other treatments. The PAE was augmented dependently on not only the concentration of H2O2 but the laser irradiation time. Electron spin resonance analysis showed that the hydroxyl radical was also generated dependently on both the concentration of H2O2 and the laser irradiation time, suggesting that the hydroxyl radicals contribute to the PAE. These results suggest that the disinfection treatment by photolysis of H2O2 induces PAE in S. aureus and S. salivarius even though they were treated for only 10-30 seconds.
巻・号 26(2)
ページ 92-100
公開日 2014-4-1
DOI 10.1179/1973947813Y.0000000114
PII joc284
PMID 24091288
MeSH Bacteria / drug effects* Disinfection / methods* Hydrogen Peroxide / pharmacology* Photolysis
IF 1.661
引用数 4
WOS 分野 PATHOLOGY PHARMACOLOGY & PHARMACY INFECTIOUS DISEASES ONCOLOGY
リソース情報
一般微生物 JCM 2413 JCM 5707