| RRC ID |
34444
|
| Author |
Roy U, Islam MR, Nagao J, Iida H, Mahin AA, Li M, Zendo T, Nakayama J, Sonomoto K.
|
| Title |
Bactericidal activity of nukacin ISK-1: an alternative mode of action.
|
| Journal |
Biosci Biotechnol Biochem
|
| Abstract |
We previously reported bacteriostatic action of nukacin ISK-1 against Bacillus subtilis JCM 1465(T). Here, we found its bactericidal activity against Micrococcus luteus DSM 1790 and Staphylococcus simulans 22, showing decrease in cell viability, cell lysis, and dissipation of the membrane potential. Moreover, leakage of small molecules such as K(+), suggested the formation of small-sized or specific K(+)-conducting-pores by nukacin ISK-1.
|
| Volume |
78(7)
|
| Pages |
1270-3
|
| Published |
2014-1-1
|
| DOI |
10.1080/09168451.2014.918485
|
| PMID |
25229869
|
| MeSH |
Anti-Bacterial Agents / isolation & purification
Anti-Bacterial Agents / pharmacology*
Bacteria / drug effects
Bacteriocins / isolation & purification
Bacteriocins / pharmacology*
|
| IF |
1.516
|
| Times Cited |
6
|
|
WOS Category
|
FOOD SCIENCE & TECHNOLOGY
BIOTECHNOLOGY & APPLIED MICROBIOLOGY
CHEMISTRY, APPLIED
BIOCHEMISTRY & MOLECULAR BIOLOGY
|
| Resource |
| General Microbes |
JCM 1157
JCM 1465
JCM 5802
JCM 5890 |
