RRC ID 3509
Author Bao Y, Yamano Y, Morishima I.
Title Induction of hemolin gene expression by bacterial cell wall components in eri-silkworm, Samia cynthia ricini.
Journal Comp Biochem Physiol B Biochem Mol Biol
Abstract A cDNA clone encoding hemolin was isolated from fat body of immunized Samia cynthia ricini larvae based on subtractive suppression hybridization method. The cDNA encodes 413 amino acid residue open reading frame with an 18 residue predicted signal peptide. The expression of the gene was strongly induced in fat body and midgut by an injection of bacterial cells or peptidoglycans, but very weakly by lipopolysaccharide. The mRNA expression in the fat body was detected as early as 3 h post-injection, and reached the peak level at 12 h.
Volume 146(1)
Pages 147-51
Published 2007-1-1
DOI 10.1016/j.cbpb.2006.10.092
PII S1096-4959(06)00360-5
PMID 17126583
MeSH Animals Bacteria / chemistry Bombyx / genetics* Bombyx / metabolism Fat Body / metabolism Gastrointestinal Tract / metabolism Gene Expression Regulation / drug effects Gene Expression Regulation / physiology Immunoglobulins / biosynthesis Immunoglobulins / genetics* Insect Proteins / biosynthesis Insect Proteins / genetics* Open Reading Frames* Peptidoglycan / chemistry Peptidoglycan / pharmacology* RNA, Messenger / biosynthesis RNA, Messenger / genetics
IF 2.219
Times Cited 16
Silkworms Samia cynthia ricini