| RRC ID |
3510
|
| 著者 |
Bao Y, Yamano Y, Morishima I.
|
| タイトル |
Beta-1,3-glucan inducible expression of prophenoloxidase-activating proteinase from eri-silkworm, Samia cynthia ricini.
|
| ジャーナル |
Comp Biochem Physiol B Biochem Mol Biol
|
| Abstract |
A cDNA clone encoding possible prophenoloxidase-activating serine protease (PAP) was isolated by screening the cDNA library from immunized larval fat body of the wild silkmoth, Samia cynthia ricini. The cDNA encodes a 438 amino acid open reading frame with a predicted 20 residue signal peptide. Samia PAP has high sequence similarity to Bombyx mori and Manduca sexta PAPs, which contain two amino terminal clip domains followed by a carboxyl-terminal catalytic domain. The expression of the gene was barely detectable in the fat body of naive larvae, but induced after injection of the larvae with beta-1,3-glucans or bacterial cells.
|
| 巻・号 |
147(1)
|
| ページ |
45-8
|
| 公開日 |
2007-5-1
|
| DOI |
10.1016/j.cbpb.2006.12.016
|
| PII |
S1096-4959(07)00010-3
|
| PMID |
17307003
|
| MeSH |
Amino Acid Sequence
Animals
Base Sequence
Bombyx / enzymology*
DNA, Complementary / genetics
DNA, Complementary / isolation & purification
Enzyme Induction / drug effects
Molecular Sequence Data
Sequence Analysis, DNA
Sequence Homology, Amino Acid
Serine Endopeptidases / biosynthesis*
Serine Endopeptidases / chemistry
Serine Endopeptidases / genetics*
beta-Glucans / pharmacology*
|
| IF |
2.219
|
| 引用数 |
6
|
|
WOS 分野
|
ZOOLOGY
BIOCHEMISTRY & MOLECULAR BIOLOGY
|
| リソース情報 |
| カイコ |
Samia cynthia ricini |
