RRC ID 35389
Author Sato T, Yoshida S, Hoshino H, Tanno M, Nakajima M, Hoshino T.
Title Sesquarterpenes (C35 terpenes) biosynthesized via the cyclization of a linear C35 isoprenoid by a tetraprenyl-β-curcumene synthase and a tetraprenyl-β-curcumene cyclase: identification of a new terpene cyclase.
Journal J Am Chem Soc
Abstract In this study, mono- and pentacyclic C(35) terpenes from Bacillus subtilis were biosynthesized via the cyclization of C(35) isoprenoid using purified enzymes, including the first identified new terpene cyclase that shows no sequence homology to any of the known terpene cyclases. On the basis of these findings, we propose that these C(35) terpenes should be called the new family of "sesquarterpenes."
Volume 133(25)
Pages 9734-7
Published 2011-6-29
DOI 10.1021/ja203779h
PMID 21627333
MeSH Bacillus subtilis / enzymology* Bacillus subtilis / metabolism Curcumin / analogs & derivatives Cyclization Enzymes / metabolism* Terpenes* / metabolism
IF 14.695
Times Cited 25
Prokaryotes E. coli NA