RRC ID 35392
Author Yamamoto K, Oshima T, Nonaka G, Ito H, Ishihama A.
Title Induction of the Escherichia coli cysK gene by genetic and environmental factors.
Journal FEMS Microbiol Lett
Abstract Cysteine synthase A encoded by cysK catalyzes the synthesis of cysteine from O-acetylserine. Expression of cysK in Escherichia coli is under the control of CysB, a LysR family transcription factor. Herein we showed that the expression of cysK is regulated by several genetic and environmental factors in addition to CysB: two genetic factors, OmpR and CysE, and lithium. Based on the findings, we constructed the high-level expression system of cysK.
Volume 323(1)
Pages 88-95
Published 2011-10-1
DOI 10.1111/j.1574-6968.2011.02364.x
PMID 22092684
MeSH Bacterial Proteins / metabolism Cysteine Synthase / biosynthesis* Escherichia coli / enzymology* Escherichia coli / genetics Escherichia coli Proteins / biosynthesis* Escherichia coli Proteins / metabolism Gene Expression Regulation, Bacterial* Gene Expression Regulation, Enzymologic* Lithium / metabolism Serine O-Acetyltransferase / metabolism Trans-Activators / metabolism Transcriptional Activation*
IF 1.987
Times Cited 9
WOS Category MICROBIOLOGY
Resource
Prokaryotes E. coli