論文 - 詳細
| RRC ID | 35426 |
|---|---|
| 著者 | Oh YK, Raj SM, Jung GY, Park S. |
| タイトル | Current status of the metabolic engineering of microorganisms for biohydrogen production. |
| ジャーナル | Bioresour Technol |
| Abstract |
The improvement of H2 production capabilities of hydrogen (H2)-producing microorganisms is a challenging issue. Microorganisms have evolved for fast growth and substrate utilization rather than H2 production. To develop good H2-producing biocatalysts, many studies have focused on the redirection and/or reconstruction of cellular metabolisms. These studies included the elimination of enzymes and carbon pathways interfering or competing with H2 production, the incorporation of non-native metabolic pathways leading to H2 production, the utilization of various carbon substrates, the rectification of H2-producting enzymes (nitrogenase and hydrogenase) and photophosphorylation systems, and in silico pathway flux analysis, among others. Owing to these studies, significant improvements in the yield and rate of H2 production, and in the stability of H2 production activity, were reached. This review presents and discusses the recent developments in biohydrogen production, with a focus on metabolic pathway engineering. |
| 巻・号 | 102(18) |
| ページ | 8357-67 |
| 公開日 | 2011-9-1 |
| DOI | 10.1016/j.biortech.2011.04.054 |
| PII | S0960-8524(11)00568-2 |
| PMID | 21733680 |
| MeSH | Bacteria / metabolism* Biofuels / analysis* Fermentation / physiology Hydrogen / metabolism* Metabolic Engineering / trends* Photolysis |
| IF | 7.539 |
| 引用数 | 89 |
| WOS 分野 | BIOTECHNOLOGY & APPLIED MICROBIOLOGY AGRICULTURAL ENGINEERING ENERGY & FUELS |
| オルトメトリクス指標 |
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| 各媒体での言及数の合計 | 0 |
| リソース情報 | |
| 原核生物(大腸菌) | NA |