論文 - 詳細
| RRC ID | 36237 |
|---|---|
| 著者 | Guo C, Du Y, Yuan D, Li M, Gong H, Gong Z, Liu L. |
| タイトル | A conditioned visual orientation requires the ellipsoid body in Drosophila. |
| ジャーナル | Learn Mem |
| Abstract |
Orientation, the spatial organization of animal behavior, is an essential faculty of animals. Bacteria and lower animals such as insects exhibit taxis, innate orientation behavior, directly toward or away from a directional cue. Organisms can also orient themselves at a specific angle relative to the cues. In this study, using Drosophila as a model system, we established a visual orientation conditioning paradigm based on a flight simulator in which a stationary flying fly could control the rotation of a visual object. By coupling aversive heat shocks to a fly's orientation toward one side of the visual object, we found that the fly could be conditioned to orientate toward the left or right side of the frontal visual object and retain this conditioned visual orientation. The lower and upper visual fields have different roles in conditioned visual orientation. Transfer experiments showed that conditioned visual orientation could generalize between visual targets of different sizes, compactness, or vertical positions, but not of contour orientation. Rut-Type I adenylyl cyclase and Dnc-phosphodiesterase were dispensable for visual orientation conditioning. Normal activity and scb signaling in R3/R4d neurons of the ellipsoid body were required for visual orientation conditioning. Our studies established a visual orientation conditioning paradigm and examined the behavioral properties and neural circuitry of visual orientation, an important component of the insect's spatial navigation. |
| 巻・号 | 22(1) |
| ページ | 56-63 |
| 公開日 | 2014-1-1 |
| DOI | 10.1101/lm.036863.114 |
| PII | 22/1/56 |
| PMID | 25512578 |
| PMC | PMC4274327 |
| MeSH | Adenylyl Cyclases / metabolism Animals Animals, Genetically Modified Conditioning, Psychological / physiology* Cyclic AMP / metabolism Drosophila / physiology* Drosophila Proteins / metabolism Flight, Animal / physiology* Hot Temperature Male Neurons / physiology Orientation / physiology* Physical Stimulation Psychomotor Performance / physiology* Rotation Visual Fields Visual Perception / physiology* |
| IF | 2.359 |
| 引用数 | 8 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 1 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ショウジョウバエ | NP1373 (DGRC#112656) NP6510 (DGRC#113956) NP2320 (DGRC#104157) |