RRC ID 36503
著者 Chao ZC, Nagasaka Y, Fujii N.
タイトル Cortical network architecture for context processing in primate brain.
ジャーナル Elife
Abstract Context is information linked to a situation that can guide behavior. In the brain, context is encoded by sensory processing and can later be retrieved from memory. How context is communicated within the cortical network in sensory and mnemonic forms is unknown due to the lack of methods for high-resolution, brain-wide neuronal recording and analysis. Here, we report the comprehensive architecture of a cortical network for context processing. Using hemisphere-wide, high-density electrocorticography, we measured large-scale neuronal activity from monkeys observing videos of agents interacting in situations with different contexts. We extracted five context-related network structures including a bottom-up network during encoding and, seconds later, cue-dependent retrieval of the same network with the opposite top-down connectivity. These findings show that context is represented in the cortical network as distributed communication structures with dynamic information flows. This study provides a general methodology for recording and analyzing cortical network neuronal communication during cognition.
巻・号 4
公開日 2015-9-29
DOI 10.7554/eLife.06121
PMID 26416139
PMC PMC4584448
MeSH Animals Brain Mapping Cerebral Cortex / physiology* Cognition* Electrocorticography Haplorhini Memory Nerve Net / physiology* Perception Photic Stimulation
IF 7.08
引用数 4
リソース情報
ニホンザル