論文 - 詳細
| RRC ID | 36816 |
|---|---|
| 著者 | Nonomura K, Nakano M, Eiguchi M, Suzuki T, Kurata N. |
| タイトル | PAIR2 is essential for homologous chromosome synapsis in rice meiosis I. |
| ジャーナル | J Cell Sci |
| Abstract |
The PAIR2 gene is required for homologous chromosome synapsis at meiosis I in rice (Oryza sativa L.) and encodes a HORMA-domain protein that is homologous to Saccharomyces cerevisiae HOP1 and Arabidopsis ASY1. Immunocytological and electron microscopic analyses indicate that PAIR2 proteins associate with axial elements (AEs) at leptotene and zygotene, and is removed from the AEs of arm regions when homologous chromosomes have been synapsed. Immunocytology against a centromeric histone H3 variant revealed that PAIR2 remains at centromeres until diakinesis, by which time the homologous centromeres had already been synapsed. However, neither precocious segregation of sister chromatids nor kinetochore dysfunction is observed, and AEs are normally assembled in the mutant. In the pair2-null mutant, homologous chromosome synapsis is completely eliminated. This study provides the first description of AE-associated protein in monocot plants and indicates that PAIR2 plays an essential role in promoting homologous chromosome synapsis. However, PAIR2 does not play a role in AE formation, sister chromatid cohesion at centromeres or kinetochore assembly in meiosis I of rice. |
| 巻・号 | 119(Pt 2) |
| ページ | 217-25 |
| 公開日 | 2006-1-15 |
| DOI | 10.1242/jcs.02736 |
| PII | 119/2/217 |
| PMID | 16410547 |
| MeSH | Cell Nucleus / metabolism Cell Nucleus / ultrastructure Chromosome Pairing* Chromosomes, Plant / metabolism Chromosomes, Plant / ultrastructure DNA-Binding Proteins / genetics DNA-Binding Proteins / metabolism* Genes, Plant* Meiosis / physiology* Oryza / cytology Oryza / genetics* Plant Proteins / genetics Plant Proteins / metabolism* Saccharomyces cerevisiae Proteins / genetics Saccharomyces cerevisiae Proteins / metabolism |
| IF | 4.573 |
| 引用数 | 99 |
| WOS 分野 | CELL BIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | Patent(IFI CLAIMS) |
| 各媒体での言及数の合計 | 1 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| イネ | Sterile strain (STER-NIG0007) (PAIR2) |