RRC ID 37091
著者 Loh XJ, Wu YL.
タイトル Cationic star copolymers based on β-cyclodextrins for efficient gene delivery to mouse embryonic stem cell colonies.
ジャーナル Chem Commun (Camb)
Abstract A cationic star copolymer with a β-cyclodextrin core was developed for nonviral gene transfer to mouse embryonic stem cells (mESCs). The copolymer comprises poly(2-dimethyl aminoethyl methacrylate) as the cationic component and poly(2-hydroxyethyl methacrylate) as the non-toxic stealth component. These materials have very low toxicity and show highly efficient transfection to mESC colonies.
巻・号 51(54)
ページ 10815-8
公開日 2015-7-11
DOI 10.1039/c5cc03686k
PMID 26040469
MeSH Animals Cations / chemistry Green Fluorescent Proteins / genetics Green Fluorescent Proteins / metabolism Mice Microscopy, Fluorescence Mouse Embryonic Stem Cells / cytology Mouse Embryonic Stem Cells / metabolism* Plasmids / genetics Plasmids / metabolism Polymers / chemistry* Transfection beta-Cyclodextrins / chemistry*
IF 5.996
引用数 69
WOS 分野 CHEMISTRY, MULTIDISCIPLINARY
リソース情報
ヒト・動物細胞 EB3(AES0139)