論文 - 詳細
| RRC ID | 37091 |
|---|---|
| 著者 | Loh XJ, Wu YL. |
| タイトル | Cationic star copolymers based on β-cyclodextrins for efficient gene delivery to mouse embryonic stem cell colonies. |
| ジャーナル | Chem Commun (Camb) |
| Abstract |
A cationic star copolymer with a β-cyclodextrin core was developed for nonviral gene transfer to mouse embryonic stem cells (mESCs). The copolymer comprises poly(2-dimethyl aminoethyl methacrylate) as the cationic component and poly(2-hydroxyethyl methacrylate) as the non-toxic stealth component. These materials have very low toxicity and show highly efficient transfection to mESC colonies. |
| 巻・号 | 51(54) |
| ページ | 10815-8 |
| 公開日 | 2015-7-11 |
| DOI | 10.1039/c5cc03686k |
| PMID | 26040469 |
| MeSH | Animals Cations / chemistry Green Fluorescent Proteins / genetics Green Fluorescent Proteins / metabolism Mice Microscopy, Fluorescence Mouse Embryonic Stem Cells / cytology Mouse Embryonic Stem Cells / metabolism* Plasmids / genetics Plasmids / metabolism Polymers / chemistry* Transfection beta-Cyclodextrins / chemistry* |
| IF | 5.996 |
| 引用数 | 69 |
| WOS 分野 | CHEMISTRY, MULTIDISCIPLINARY |
| リソース情報 | |
| ヒト・動物細胞 | EB3(AES0139) |