| RRC ID |
37439
|
| 著者 |
Tomaru Y, Toyoda K, Suzuki H, Nagumo T, Kimura K, Takao Y.
|
| タイトル |
New single-stranded DNA virus with a unique genomic structure that infects marine diatom Chaetoceros setoensis.
|
| ジャーナル |
Sci Rep
|
| Abstract |
Diatoms are among the most abundant organisms in nature; however, their relationships with single-stranded DNA (ssDNA) viruses have not yet been defined in detail. We report the isolation and characterisation of a virus (CsetDNAV) that lytically infects the bloom-forming diatom Chaetoceros setoensis. The virion is 33 nm in diameter and accumulates in the nucleus of its host. CsetDNAV harbours a covalently closed-circular ssDNA genome comprising 5836 nucleotides and eight different short-complementary fragments (67-145 nucleotides), which have not been reported in other diatom viruses. Phylogenetic analysis based on the putative replicase-related protein showed that CsetDNAV was not included in the monophyly of the recently established genus Bacilladnavirus. This discovery of CsetDNAV, which harbours a genome with a structure that is unique among known viruses that infect diatoms, suggests that other such undiscovered viruses possess diverse genomic architectures.
|
| 巻・号 |
3
|
| ページ |
3337
|
| 公開日 |
2013-11-26
|
| DOI |
10.1038/srep03337
|
| PII |
srep03337
|
| PMID |
24275766
|
| PMC |
PMC3840382
|
| MeSH |
Base Sequence
DNA Viruses / genetics*
DNA Viruses / isolation & purification
DNA Viruses / pathogenicity
DNA, Circular / genetics
DNA, Single-Stranded / genetics
DNA, Viral / genetics*
Diatoms / virology*
Genome, Viral / genetics*
Phylogeny
Sequence Analysis, DNA
Viral Proteins / genetics*
Virus Assembly / physiology
Virus Replication / physiology
|
| IF |
3.998
|
| 引用数 |
18
|
|
WOS 分野
|
MICROBIOLOGY
|
| リソース情報 |
| 藻類 |
NIES-3710
NIES-3711
NIES-3712
NIES-3713 |
