RRC ID 37852
Author Nakazawa Y, Suzuki T, Fukuyama T, Katsuyama Y, Tanaka M, Yanagisawa R, Sakashita K, Shiohara M, Koike K.
Title Urinary excretion of ganciclovir contributes to improvement of adenovirus-associated hemorrhagic cystitis after allogeneic bone marrow transplantation.
Journal Pediatr Transplant
Abstract A nine-yr-old girl developed AdV-associated HC after bone marrow transplantation. Intravenous GCV markedly reduced urinary AdV DNA loads and improved clinical findings. This appeared to result partly from a high concentration of GCV in urine. GCV may be effective for AdV-induced HC without definitive disseminated infection.
Volume 13(5)
Pages 632-5
Published 2009-8-1
DOI 10.1111/j.1399-3046.2008.01027.x
PII PTR1027
PMID 18992066
MeSH Adenoviridae / metabolism* Adenoviridae Infections / diagnosis Adenoviridae Infections / urine Bone Marrow Transplantation / adverse effects* Cell Line, Tumor Child Cystitis / drug therapy* Cystitis / virology Female Ganciclovir / therapeutic use Ganciclovir / urine* Humans Immunosuppressive Agents / therapeutic use Leukemia, Myeloid, Acute / therapy* Risk Factors Transplantation, Homologous
IF 1.425
Times Cited 4
WOS Category PEDIATRICS TRANSPLANTATION
Resource
Human and Animal Cells A549(RCB0098)