論文 - 詳細
| RRC ID | 38241 |
|---|---|
| 著者 | Wang X, Ito A, Sogo Y, Li X, Oyane A. |
| タイトル | Silicate-apatite composite layers on external fixation rods and in vitro evaluation using fibroblast and osteoblast. |
| ジャーナル | J Biomed Mater Res A |
| Abstract |
A silicate-apatite layer was formed on commercially available anodically oxidized titanium rods using Na(2)SiO(3)-containing supersaturated calcium phosphate solutions. With the increase in the concentration of Na(2)SiO(3) in the supersaturated calcium phosphate solutions, the amounts of silicon that precipitated on the titanium rods increased from 0 to 0.07 +/- 0.02 microg/cm(2); meanwhile, the amounts of calcium and phosphorus that precipitated on the titanium rods decreased from 11.6 +/- 1.6 and 5.7 +/- 2.0 microg/cm(2) to 2.6 +/- 0.5 and 3.0 +/- 1.0 microg/cm(2), respectively. The present silicate-apatite composite layers, which demonstrated increased fibroblastic proliferation and osteoblastic proliferation and differentiation in vitro, are promising as coating layers on external fixation pins for decreasing the pin tract infection rate in vivo. |
| 巻・号 | 92(3) |
| ページ | 1181-9 |
| 公開日 | 2010-3-1 |
| DOI | 10.1002/jbm.a.32436 |
| PMID | 19322819 |
| MeSH | Animals Apatites / chemistry Apatites / pharmacology* External Fixators* Fibroblasts / cytology In Vitro Techniques Mice NIH 3T3 Cells Osteoblasts / cytology Silicates / chemistry Silicates / pharmacology* |
| IF | 3.525 |
| 引用数 | 22 |
| WOS 分野 | ENGINEERING, BIOMEDICAL MATERIALS SCIENCE, BIOMATERIALS |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 最多言及媒体 | Patent(IFI CLAIMS) |
| 各媒体での言及数の合計 | 1 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ヒト・動物細胞 | MC3T3-E1(RCB1126) |