| RRC ID |
38336
|
| Author |
Sone Y, Kudo Y, Oba R, Otsuka Y.
|
| Title |
Effects of oxygen concentration on the expression of an antioxidant gene in HepG2.
|
| Journal |
Biosci Biotechnol Biochem
|
| Abstract |
To clarify the effects of O(2) concentration (cO(2)) on antioxidant gene expression in human hepatocytes, mRNA expression of HepG2 cells cultured at 1, 3, and 5% cO(2) and atmospheric gas-phase, was measured. The expression of some genes fluctuated depending on the cO(2) in the incubator. This indicates that cO(2) is a critically important factor in the investigation of human biological mechanisms.
|
| Volume |
74(6)
|
| Pages |
1267-70
|
| Published |
2010-1-1
|
| DOI |
10.1271/bbb.90837
|
| PII |
JST.JSTAGE/bbb/90837
|
| PMID |
20530896
|
| MeSH |
Antioxidants / metabolism*
Dose-Response Relationship, Drug
Gene Expression Regulation / drug effects*
Hep G2 Cells
Humans
Oxygen / pharmacology*
RNA, Messenger / genetics
RNA, Messenger / metabolism
|
| IF |
1.516
|
| Times Cited |
1
|
|
WOS Category
|
BIOCHEMISTRY & MOLECULAR BIOLOGY
BIOTECHNOLOGY & APPLIED MICROBIOLOGY
CHEMISTRY, APPLIED
FOOD SCIENCE & TECHNOLOGY
|
| Resource |
| Human and Animal Cells |
|
