Reference - Detail
RRC ID | 38337 |
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Author | Fujimori H, Hisama M, Shibayama H, Kawase A, Iwaki M. |
Title | Inhibitory effects of phytoncide solution on melanin biosynthesis. |
Journal | Biosci Biotechnol Biochem |
Abstract |
To determine the component-activity relationships of phytoncide solutions on inhibitory activity in melanin biosynthesis, four types of phytoncide solution (A-type, AB-type, D-type, and G-type) were evaluated for inhibition of mushroom tyrosinase activity and melanin synthesis on murine B-16 melanoma cells and a human reconstituted skin model. The A-type, AB-type, D-type, and G-type of phytoncide solution treatment resulted in significant inhibition of tyrosinase activity. The amount of melanin was increased by treatment with phytoncide solutions in a concentration-dependent manner on murine B-16 melanoma cells without affecting cell growth. Furthermore, phytoncide solutions also suppressed melanin synthesis in a concentration-dependent manner on a human reconstituted skin model. These effects of A-type solution were superior to those of other solutions. |
Volume | 74(5) |
Pages | 918-22 |
Published | 2010-1-1 |
DOI | 10.1271/bbb.90700 |
PII | JST.JSTAGE/bbb/90700 |
PMID | 20460709 |
MeSH | Agaricales / enzymology Animals Antioxidants / chemistry Antioxidants / pharmacology Cell Line, Tumor Humans Melanins / biosynthesis* Mice Monophenol Monooxygenase / antagonists & inhibitors Plant Extracts / chemistry* Plant Extracts / pharmacology* Skin / drug effects Skin / metabolism Solutions Volatilization |
IF | 1.516 |
Times Cited | 6 |
WOS Category | FOOD SCIENCE & TECHNOLOGY CHEMISTRY, APPLIED BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY |
Resource | |
Human and Animal Cells |