論文 - 詳細
| RRC ID | 38714 |
|---|---|
| 著者 | Yokoyama K, Suzuki H, Yasumoto K, Tomita Y, Shibahara S. |
| タイトル | Molecular cloning and functional analysis of a cDNA coding for human DOPAchrome tautomerase/tyrosinase-related protein-2. |
| ジャーナル | Biochim Biophys Acta |
| Abstract |
We have cloned the cDNAs encoding tyrosinase-related protein-2 (TRP-2) from a human melanoma cDNA library. Transient expression of the isolated cDNA in HeLa cells established that TRP-2 is DOPAchrome tautomerase. Human TRP-2/DOPAchrome tautomerase is composed of 519 amino acids with a molecular weight of 59,000 and has about 84% identity with the mouse counterpart. |
| 巻・号 | 1217(3) |
| ページ | 317-21 |
| 公開日 | 1994-4-6 |
| DOI | 10.1016/0167-4781(94)90292-5 |
| PII | 0167-4781(94)90292-5 |
| PMID | 8148378 |
| MeSH | Amino Acid Sequence Base Sequence Cloning, Molecular DNA, Complementary / biosynthesis* DNA, Complementary / chemistry Gene Expression HeLa Cells Humans Intramolecular Oxidoreductases* Isomerases / genetics* Melanoma / genetics Molecular Sequence Data Sequence Alignment |
| IF | 3.411 |
| 引用数 | 101 |
| WOS 分野 | BIOPHYSICS BIOCHEMISTRY & MOLECULAR BIOLOGY |
| リソース情報 | |
| ヒト・動物細胞 | HMV-II(RCB0777) |