| RRC ID |
39385
|
| Author |
Kawaii S, Tomono Y, Katase E, Ogawa K, Yano M.
|
| Title |
Antiproliferative effects of the readily extractable fractions prepared from various citrus juices on several cancer cell lines.
|
| Journal |
J Agric Food Chem
|
| Abstract |
To eliminate the masking effect by flavonoid glycosides, which comprise approximately 70% of conventionally prepared sample, the readily extractable fraction from Citrus juice, which was prepared by adsorbing on HP-20 resin and eluting with ethanol and acetone from the resin, was subjected to antiproliferative tests against several cancer cell lines. Screening of 34 Citrus juices indicated that King (Citrus nobilis) strongly inhibited proliferation of all cancer cell lines examined. Sweet lime and Kabuchi inhibited three of the four cancer cell lines. In contrast, these samples were substantially less cytotoxic toward normal human cell lines.
|
| Volume |
47(7)
|
| Pages |
2509-12
|
| Published |
1999-7-1
|
| DOI |
10.1021/jf9812228
|
| PII |
jf9812228
|
| PMID |
10552518
|
| MeSH |
Antineoplastic Agents, Phytogenic / isolation & purification
Antineoplastic Agents, Phytogenic / pharmacology*
Beverages / analysis*
Cell Division / drug effects*
Citrus / chemistry*
Citrus / classification
Humans
Species Specificity
Tumor Cells, Cultured
|
| IF |
4.192
|
| Times Cited |
26
|
|
WOS Category
|
AGRICULTURE, MULTIDISCIPLINARY
CHEMISTRY, APPLIED
FOOD SCIENCE & TECHNOLOGY
|
| Resource |
| Human and Animal Cells |
TGBC11TKB(RCB1148)
A549(RCB0098)
B16 melanoma 4A5(RCB0557)
CCRF-HSB-2(RCB0016) |
