RRC ID 39824
Author Matsufuji M, Nagamatsu Y, Yoshimoto A.
Title Effects of bacterial glyceroglycolipid M874B on growth and TPA-induced differentiation of HL60 cells.
Journal Biosci Biotechnol Biochem
Abstract Bacterial monogalactosyldiacylglycerol M874B (MGDAG), which protects against oxygen radicals, was found to increase the growth of the human promyelocytic leukemia cell HL60 when added to the cell culture, but suppresses the 12-O-tetradecanoyl phorbol-13-acetate-induced differentiation. Analogous MGDAG, S365B had weak, but similar effects. These activities were not observed with analogous plant glyceroglycolipids and diacylglycerol.
Volume 64(6)
Pages 1302-4
Published 2000-6-1
DOI 10.1271/bbb.64.1302
PMID 10923809
MeSH Actinomycetales / chemistry Cell Differentiation / drug effects* Cell Division / drug effects* Free Radical Scavengers / pharmacology* Galactolipids* Galactose / pharmacology* Glycerides / pharmacology* Glycolipids / pharmacology* HL-60 Cells Humans Tetradecanoylphorbol Acetate / pharmacology
IF 1.516
Times Cited 3
WOS Category CHEMISTRY, APPLIED FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY
Resource
Human and Animal Cells HL60(RCB0041)