RRC ID 40072
Author Eguchi H, Toibana T, Hotta F, Miyamoto T, Mitamura Y, Yaguchi T.
Title Severe fungal sclerokeratitis caused by Metarhizium anisopliae: a case report and literature review.
Journal Mycoses
Abstract To date, there has been only one published report on the infectious sclerokeratitis caused by Metarhizium anisopliae, which is an entomopathogenic fungus. Regarding corneal infection, three reports have been published to date. Although the prognoses of the corneal infections are favourable, prognosis when scleral infection is involved is very poor. A 76-year-old patient presented with foreign body sensation in the left eye. Microscopic examination with Fungi Flora Y staining of the corneal scraping revealed fungal infection. The conjunctiva was melted by the infection over a wide area. Although intensive medications were administered, an emergency surgery was necessary because scleral thinning, corneal perforation and lens prolapse occurred. The fungal isolate was identified as M. anisopliae by sequencing the internal transcribed spacer region. Herein, we report the second known case worldwide of M. anisopliae sclerokeratitis, and we review the literature related to the ocular infections.
Volume 58(2)
Pages 88-92
Published 2015-2-1
DOI 10.1111/myc.12279
PMID 25590990
MeSH Aged Antifungal Agents / pharmacology Antifungal Agents / therapeutic use Corneal Perforation / etiology Diagnostic Errors Echinocandins / pharmacology Eye Infections, Fungal / microbiology* Eye Infections, Fungal / therapy Humans Japan Keratitis / microbiology* Keratitis / therapy Lipopeptides / pharmacology Male Metarhizium / drug effects Metarhizium / isolation & purification* Metarhizium / ultrastructure Micafungin Scleritis / microbiology* Scleritis / therapy
IF 3.575
Times Cited 14
WOS Category DERMATOLOGY MYCOLOGY
Resource
Pathogenic microorganisms IFM 61840