Reference - Detail
| RRC ID | 4057 |
|---|---|
| Author | Mori Y, Kimura S, Saotome A, Kasai N, Sakaguchi N, Uchiyama Y, Ishibashi T, Yamamoto T, Chiku H, Sakaguchi K. |
| Title | Plastid DNA polymerases from higher plants, Arabidopsis thaliana. |
| Journal | Biochem Biophys Res Commun |
| Abstract |
Previously, we described a novel DNA polymerase, designated as OsPolI-like, from rice. The OsPolI-like showed a high degree of sequence homology with the DNA polymerase I of cyanobacteria and was localized in the plastid. Here, we describe two PolI-like polymerases, designated as AtPolI-like A and AtPolI-like B, from Arabidopsis thaliana. In situ hybridization analysis demonstrated expression of both mRNAs in proliferating tissues such as the shoot apical meristem. Analysis of the localizations of GFP fusion proteins showed that AtPolI-like A and AtPolI-like B were localized to plastids. AtPolI-like B expression could be induced by exposure to the mutagen H(2)O(2). These results suggested that AtPolI-like B has a role in the repair of oxidation-induced DNA damage. Our data indicate that higher plants possess two plastid DNA polymerases that are not found in animals and yeasts. |
| Volume | 334(1) |
| Pages | 43-50 |
| Published | 2005-8-19 |
| DOI | 10.1016/j.bbrc.2005.06.052 |
| PII | S0006-291X(05)01264-7 |
| PMID | 15993837 |
| MeSH | Amino Acid Sequence Arabidopsis / genetics* Arabidopsis / metabolism* DNA Polymerase I / chemistry DNA Polymerase I / genetics* DNA Polymerase I / metabolism* Molecular Sequence Data Plant Structures / genetics Plant Structures / metabolism Plastids / genetics* Plastids / metabolism* Sequence Homology, Amino Acid Tissue Distribution |
| IF | 2.985 |
| Times Cited | 36 |
| WOS Category | BIOPHYSICS BIOCHEMISTRY & MOLECULAR BIOLOGY |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | Patent(IFI CLAIMS) |
| Total number of mentions | 4 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Arabidopsis / Cultured plant cells, genes | pda05342 |