Reference - Detail
| RRC ID | 41499 |
|---|---|
| Author | Wang LQ, Min BS, Li Y, Nakamura N, Qin GW, Li CJ, Hattori M. |
| Title | Annonaceous acetogenins from the leaves of Annona montana. |
| Journal | Bioorg Med Chem |
| Abstract |
A novel Annonaceous acetogenin, montanacin F, with a new type of terminal lactone unit, was isolated from the leaves of Annona montana. Its structure was determined on the basis of spectral evidences and chemical methods, and a possible biosynthetic pathway was discussed. In addition, the cytotoxicity of montanacin F was evaluated in vitro against Lewis lung carcinoma (LLC) tumor cell lines. Furthermore, the previously isolated cytotoxic acetogenin annonacin against LLC was examined for in vivo antitumor activity with LLC tumor cells. |
| Volume | 10(3) |
| Pages | 561-5 |
| Published | 2002-3-1 |
| DOI | 10.1016/s0968-0896(01)00303-0 |
| PII | S0968089601003030 |
| PMID | 11814843 |
| MeSH | Animals Annonaceae / chemistry* Antineoplastic Agents / chemistry* Antineoplastic Agents / isolation & purification Antineoplastic Agents / pharmacology Carcinoma, Lewis Lung / drug therapy Female Furans / chemistry* Furans / isolation & purification Furans / pharmacology Injections, Intraperitoneal Lactones / chemistry* Lactones / isolation & purification Lactones / pharmacology Mice Plant Leaves / chemistry Tumor Cells, Cultured / transplantation |
| IF | 3.073 |
| Times Cited | 21 |
| WOS Category | CHEMISTRY, ORGANIC CHEMISTRY, MEDICINAL BIOCHEMISTRY & MOLECULAR BIOLOGY |
| Altmetric score |
オルトメトリクス指標項目
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| Total number of mentions | 0 |
| Resource | |
| Human and Animal Cells | LLC(RCB0558) |